A Transduction-like Process within a Single Strain of Pseudomonas aeruginosa

A transduction-like process within a single strain of Pseudomonas aeruginosa.

Three processes of genetic exchange have been demonstrated €or bacteria. First, there was the process of pneumococcal transformation originally described by Alloway (1932). The active principle was shown to be a deoxyribonucleic acid by Avery, MacLeod & McCarty (1944). Secondly, a sexual process was described by Lederberg & Tatum (1946) for the K12 strain of Escherichia coli. Thirdly, Zinder & ...

Genotypic Diversity within a Single Pseudomonas aeruginosa Strain Commonly Shared by Australian Patients with Cystic Fibrosis.

In cystic fibrosis (CF), Pseudomonas aeruginosa undergoes intra-strain genotypic and phenotypic diversification while establishing and maintaining chronic lung infections. As the clinical significance of these changes is uncertain, we investigated intra-strain diversity in commonly shared strains from CF patients to determine if specific gene mutations were associated with increased antibiotic ...

Does a single Pseudomonas aeruginosa

Patients with chronic obstructive pulmonary disease (COPD) often suffer from acute exacerbations (AECOPD) of their disease, which have a significant impact on their health status [1]. Evidence suggests that ,50% of these exacerbations are attributable to bacteria [2]. Pseudomonas aeruginosa can cause AECOPD and is associated with reduced survival in cystic fibrosis (CF) and bronchiectasis [3, 4...

Pseudomonas aeruginosa acquires biofilm-like properties within airway epithelial cells.

Pseudomonas aeruginosa can notably cause both acute and chronic infection. While several virulence factors are implicated in the acute phase of infection, advances in understanding bacterial pathogenesis suggest that chronic P. aeruginosa infection is related to biofilm formation. However, the relationship between these two forms of disease is not well understood. Accumulating evidence indicate...

Single Cells of Pseudomonas aeruginosa